The Department of Nursing traces its roots to the College of Nursing of the Mariano Marcos Memorial College of Science and Technology (MMCST) which was opened on June 20, 1976 by virtue of Board Resolution No. 140, s. 1976 with Dr. Deborah R. Abara as the first dean. At present, the Department of Nursing is one of the academic departments of the College of Health Sciences.
Graduates of the Nursing program are provided with sound academic foundation through excellent instruction and trainings that enable them to perform well in the Nurse Licensure Examination. Their outstanding performances in the Nurse Licensure Examinations given by the Board of Nursing of the Professional Regulation Commission have always been above the national passing percentage, thus, placing MMSU in the list of Top Performing Schools in Nursing. The commendable performance of the nursing graduates in the most recent Nurse Licensure Examination has once again added laurels to the University as Mr. Anwar Garaza, a 2012 graduate, emerged as 9th placer in the June 2012 Nurse Licensure Examination. The MMSU passing rate in the said exam is 93.20% which is way above the national passing rate of 45.69%